Cylicodiscus gabunensis and Scoparia dulcis: Potential sources of new antifilaricidal agents

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منابع مشابه

A cytotoxic flavone from Scoparia dulcis L.

In a continuation of our studies on biologically active substances of the Paraguayan crude drug,"Typychd kuratir(Scoparia dulcis L.,Scrophulariaceae),1)we isolated a polyoxygenated flavone(1),which was found to exhibit cytotoxicity against human cultured cells such as HeLa 229,2)HeLa S3,3)HEp-2,4)FL,5)Chang liver6)and intestine 4077)cells. Some flavonoids have been reported to be cytotoxic to K...

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Protective Effect of Scoparia dulcis on Brain and Erythrocytes

In order to evaluate the protective effect of Scoparia dulcis L. (Scrophulariaceae), a medicinal plant known to have medico-magic power, different extracts were prepared by successive extraction with hexane (HE), chloroform (CE) and methanol (ME) and by a soaking in acetone (80%). These extracts were checked for their protective role against neuroinflammation and erythrocytes haemolysis. They e...

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Anti-hyperglycemic effect of Scoparia dulcis in streptozotocin induced diabetes

Aqueous extract of Scoparia dulcis could significantly reduce blood sugar levels in white rats which had been previously induced with diabetes by streptozotocin. Extract was administered at doses of 125 and 250 mg/kg body weight/twice a day respectively for a period of 3 weeks. Diabetic rats had much reduced body weight than normal rats. Administration of the extracts at the dose of 250 mg/kg b...

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Evaluation of antimicrobial activity of the stem bark of Cylicodiscus gabunensis (Mimosaceae).

Ethyl acetate (EA) extract of the stem bark of Cylicodiscus gabunensis (CG) was analysed phytochemically and evaluated for its antimicrobial activity against 17 pathogenic species isolated from patient: Escherichia coli, Klebsiella pneumoniae, Shigella dysenteriae, Shigella flexneri, Morganella morganii, Proteus vulgaris, Proteus mirabilis, Salmonella typhi, Citrobacter freundii, Enterobacter c...

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Antisickling and toxicological evaluation of the leaves of Scoparia dulcis Linn (Scrophulariaceae)

BACKGROUND Scoparia dulcis Linn (Scrophulariaceae) together with other medicinal plants serve as antisickling remedies in Africa. This study was aimed at investigating the antisickling activity of the leaves of the plant as well as establishing the toxicological profile. METHOD Chemical tests were employed in phytochemical investigations. Evaluation of the antisickling activity involved the i...

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ژورنال

عنوان ژورنال: International Journal of Infectious Diseases

سال: 2020

ISSN: 1201-9712

DOI: 10.1016/j.ijid.2020.09.819